Difference Between Reference Standard And Working Standard. Then we should calculate linearity and validity if they are ok we can use the tested material as working standard. The working standard is what you use to do your work let s say you are performing an hplc purity and degradation assay on aspirin tablets for your client.
What is deference b w the working standard and reference standard. A reference electrode is an electrode which has a stable and well known electrode potential the high stability of the electrode potential is usually reached by employing a redox system with constant buffered or saturated concentrations of each participant of the redox reaction. But the qualification style is difference from one another.
A working standard i e in house or secondary standard is a standard that is qualified against and used instead of the reference standard.
The standards are commonly grouped into two groups. Answer minoo as i know we should measure the assay against refrence standards at least two times. Reference standards and working standards are same thing and reference standards are of higher quality or precision and we use these standards very little whereas working standards are of lower precision and we use them in our daily routine. Normally reference standards are used to calibrate the working standards.
